Case study (14)- Eosinophilia in carcinoid syndrome

History:

A 65-year-old woman was subjected to surgery to remove multiple metastases of a gastrointestinal tumor.

RBC:4.04 X 106/μL (4-5.5 X 106/μL)

HGB:120 g/dL (120-174 g/dL)

HCT: 37.9 % (36-52%)

MCV: 94.1 fL (76–96 fL)

MCH: 29.8 pg (27-32 pg)

MCHC: 317 g/L (300-350 g/L)

RDWsd:37.4 fL (20-42 fL)

RDWcv: 13.3 % (0-16 %)

WBC: 5.04 X103/ μL (5–10 X 103/ μL)

Neutrophils: 2.34 X 103/μL (2-7.5 X 103/μL)

Lymphocytes: 1.13 X 103/μL (1.08–3.17 X 103/μL)

Monocytes: 0.51 X 103/μL (0.15-0.7 X 103/μL)

Eosinophils: 0.98 X 103/μL (0-0.5 X 103/μL)

Basophils: 0.07 X 103/μL (0-0.15 X 103/μL)

Neutrophils %: 46.6 % (40-75 %)

Lymphocytes %: 22.5 % (14.76-45.4 %)

Monocytes %: 10.1 % (3-7 %)

Eosinophils %: 19.5 % (0-5 %)

Basophils %: 1.3 % (0-1.5 %)

PLT: 233 X 103/μL (150-400 X 103/μL)

- Serum levels of chromogranin A, the marker of carcinoid tumors markedly exceeded the upper limit of normal.

Eosinophilia in carcinoid syndrome

- Chromogranin A levels dropped dramatically after the surgery. One month later the eosinophil count was in the normal range.